Phenylacetylcarbinol (abbreviated PAC) is an organic compound used as a chemical precursor in the synthesis of pharmaceuticals such as pseudoephedrine. A chiral molecule, generally only the laevo diastereomer of phenylacetylcarbinol (abbreviated variously as L-PAC, R-PAC, LPAC, or (R)-PAC) is used, because L-PAC transforms to (R)-(-)-pseudoephedrine—the commercially used isomer of pseudoephedrine—when processed in a reductive amination reaction.
The majority of L-PAC is generated in pharmaceutical plants in India, as an intermediate precursor in the production of pseudoephedrine.
Validated HPLC method for the determination of enantiomeric impurity of d-Pseudoephedrine sulfate.(high performance liquid chromatography)(Report)
May 01, 2009; Introduction Pseudoephedrine (commonly abbreviated as PES) is a sympathomimetic amine commonly used as a decongestant. The salts...