2C-O or is a phenethylamine of the 2C family and was first synthesized by Jansen in 1931. It is a positional isomer of the drug mescaline and is structurally similar to the drug 2C-D.
2C-O is a member of a class of chemical compounds commonly known as phenethylamines. Its full chemical name is 2-(2,4,5-trimethoxyphenyl)ethanamine; it is also known as 2,4,5-trimethoxyphenethylamine and 2,4,5-TMPEA.
Although not centrally active itself, 2,4,5-TMPEA appeared to potentiate the action of mescaline when employed as pretreatment 45 minutes prior to the administration of mescaline.
The toxicity of 2C-O is not known.
2C-O is unscheduled and unregulated in the United States, however its close similarity in structure to mescaline and 2C-B could potentially subject possession and sale of 2C-O to prosecution under the Federal Analog Act.
2C-O and all other compounds featuring in PiHKAL are Class A drugs in the United Kingdom.