is a mixture of several digestive enzymes
produced by the exocrine
cells of the pancreas
. It is composed of amylase
. This mixture is used to treat conditions in which pancreatic
secretions are deficient, such as pancreatitis
and cystic fibrosis
. It has been claimed to help with food allergies, celiac disease, autoimmune disease, cancer, and weight loss. Pancreatin is sometimes called "pancreatic acid", although it is neither a single chemical substance nor an acid.
Pancreatin contains the pancreatic enzymes trypsin, amylase, and lipase. A similar mixture of enzymes is sold as pancrelipase, which contains more active lipase enzyme than does pancreatin. The trypsin found in pancreatin works to hydrolyze proteins into oligopeptides; amylase hydrolyzes starches into oligosaccharides and the disaccharide maltose; and lipase hydrolyzes triglycerides into fatty acids and glycerols. Pancreatin is an effective enzyme supplement for replacing missing pancreatic enzymes, and aids in the digestion of foods in cases of pancreatic insufficiency.
Some contact lens cleaning solutions contain porcine pancreatin extractives to assist in the intended protein-removal process.