PSM, the acronym, may stand for the following:

In organisations:

• Palestine Solidarity Movement, a U.S.-based student organization
• Parti Sosialis Malaysia, a socialist party in Malaysia
• PlayStation Magazine, a video game magazine focused on Sony consoles
• PSM3, a UK video game magazine

In scholarship:

• Protokoly sionskix mudrecov, or the Protocols of the Sages of Zion; a series of book titles

In science:

• Plastarch Material, a biodegradable resin manufactured from cornstarch versus petroleum.
• Phase Shift Modulation, a radio communications modulation technique
• Phase-shift mask, a type of photomask in photolithography
• phenol-soluble modulin, a toxic protein produced by Methicillin-resistant Staphylococcus aureus
• PSM (pistol), a Russian semi-automatic pistol chambered in 5.45x18mm
• Perspective Shadow Map
• Platform-specific model, a model of a software or business system that is linked to a specific technological platform

In locations:

• Portsmouth International Airport at Pease in Portsmouth, New Hampshire, according to the International Air Transport Association
• El Puerto de Santa María, a city in Andalusia, Spain

In other uses:

• Poste sanitaire mobile, an initialism for a French field hospital
• Process Safety Management, an initialism for a US Occupational Safety and Health Administration safety regulation
• Platoon Sergeant Major
• Pro Stock Motorcycle, a class in motorcycle drag racing
• Professional Science Masters, a Masters Degree curriculum
• Van Westendorp's Price Sensitivity Meter
• "Paranoia Survivor Max", a song from the music video game Dance Dance Revolution Extreme
• Policy Simulation Model, a static microsimulation model of British tax and benefits system
• Public Service Medal, an Australian civil award