The Guitar Hero series' games themselves are compatible, but the connector mounted on its special controller originally was not, due to the PS3's lack of ports for PS2 accessories. With the release of third party USB-to-PS2 adapters, the games are now fully playable.
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| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| .hack//INFECTION | PS2 | Bandai | SLUS-20267 | Yes | Yes |
| .hack//MUTATION | PS2 | Bandai | SLUS-20562 | Yes | Yes |
| .hack//OUTBREAK | PS2 | Bandai | SLUS-20563 | Yes | Yes |
| .hack//QUARANTINE | PS2 | Bandai | SLUS-20564 | Yes | Yes |
| .hack//G.U. Vol.1//Rebirth | PS2 | Bandai | SLUS-21258 | Yes | Yes |
| .hack//G.U. Vol.2//Reminisce | PS2 | Bandai | SLUS-21488 | Yes | Yes |
| .hack//G.U. Vol.3//Redemption | PS2 | Bandai | SLUS-21489 | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| 18 Wheeler: American Pro Trucker | PS2 | Acclaim Entertainment | SLUS-20210 | Yes | Yes |
| 187 Ride or Die | PS2 | Ubisoft | SLUS-21116 | Yes | No |
| 24: The Game | PS2 | 2K Games | SLUS-21268 | Yes | Yes |
| 25 to Life | PS2 | Eidos Interactive | SLUS-21016 | Yes | Yes |
| 2002 FIFA World Cup | PS1 | EA | SLUS-01449 | Yes | Yes |
| 2002 FIFA World Cup | PS2 | EA | SLUS-20404 | Yes | Yes |
| 2006 FIFA World Cup | PS2 | EA | SLUS-21408 | Yes | No |
| 4x4 EVO | PS2 | Gathering of Developers | SLUS-20091 | Yes | Yes |
| 50 Cent: Bulletproof | PS2 | Vivendi | SLUS-21315 | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Ace Combat 2 | PS1 | Namco | SLUS-00404 | Yes | No |
| Ace Combat 3 | PS1 | Namco | SLUS-00972 | Yes | Yes |
| Ace Combat 04: Shattered Skies | PS2 | Namco | SLUS-20152 | Yes | Yes |
| Ace Combat 5: The Unsung War | PS2 | Namco | SLUS-20851 | Yes as of v1.10 | Yes |
| Ace Combat Zero: The Belkan War | PS2 | Namco | SLUS-21346 | Yes | Yes |
| Activision Anthology | PS2 | Activision | SLUS-20588 | Yes | Yes |
| Activision Classics | PS1 | Activision | SLUS-00777 | Yes | Yes |
| The Adventures of Cookie & Cream | PS2 | Agetec | SLUS-20170 | Yes | Yes |
| Ar tonelico: Melody of Elemia | PS2 | NIS America | SLUS-21445 | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Battlestar Galactica | PS2 | Universal | SLUS-20421 | Yes | Yes |
| The Bouncer | PS2 | Square Electronic Arts | SLUS-20069 | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Disgaea: Hour of Darkness | PS2 | Atlus Co. | N/A | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Final Fantasy X | PS2 | Square Electronic Arts | SCUS-20312GH | Yes | Yes |
| Final Fantasy X-2 | PS2 | Square Enix | SCUS-20672 | Yes | Yes |
| Final Fantasy XII | PS2 | Square Enix | SCUS-20963 | Yes | Yes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Jak and Daxter: The Precursor Legacy | PS2 | Naughty Dog | SCUS-97124GH | Yes | Plays, freezes randomly, most of the time unfreezes |
| Title | System | Publisher | Product No. | Compatible with 60GB PS3 | Compatible with 80GB PS3 |
|---|---|---|---|---|---|
| Shin Megami Tensei: Persona 3 | PS2 | Atlus | SLUS-21621 | Yes | Yes |
| Soulcalibur III | PS2 | Namco | SLUS-21216GH | Yes | Yes |
| Star Ocean: Till the End of Time | PS2 | Square Enix | SLUS-SLUS-20488 | Yes | Yes |
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