Otto Emil Franz Ulrich Busse
- February 3
) was a German pathologist
. Busse was born in Belgard
(today Białogard, Poland) and studied medicine at the University of Greifswald
, and subsequently became an assistant to Paul Grawitz
(1850-1932), (his future father-in-law) at Greifswald
. Afterwards he moved to Posen (today Poznan
, Poland), where in 1904 he became a professor of pathology. From 1911 until 1922 he was professor of pathological anatomy
at the University of Zurich
, where he died.
In 1894 Busse was the first to describe a yeast-like fungus known as Cryptococcus neoformans, which was discovered in a patient with chronic periostitis of the tibia. At the time he called the fungus Saccharomyces hominis. Infection caused by the fungus is called cryptococcosis, or sometimes Busse-Buschke disease, named in conjunction with dermatologist Abraham Buschke (1868-1943).