Because optic nerve hypoplasia involves the underdevelopment of structures located within the brain, the condition may also be found in conjunction with a constellation of hormonal imbalances and midline brain defects known as septo-optic dysplasia.
There is but a weak correlation between young maternal age, or maternal diabetes, and the occurrence of this condition. It cannot be tied in with any harmful maternal activities, but there is one study that suggests children with Fetal alcohol syndrome, or prenatal alcohol exposure, often have optic nerve hypoplasia. It has also been related to marijuana and cocaine use by pregnant mothers. While cocaine has been known to damage nerves in the fetus, recent studies have found a correlation between the optic nerve and THC. Medicinal marijuana use has most commonly been associated with glaucoma, to relieve pressure on the eyes. THC has been found to interact with a baby's eyes in the womb, thus retarding the growth of the optic nerve.
A multidisciplinary approach to educating preschool children with optic nerve hypoplasia and septo-optic nerve dysplasia.
Mar 22, 2003; Optic nerve hypoplasia (ONH) is presently the third most prevalent eye condition of children enrolled in early intervention...