, once known as Albright's calcinosis
after Fuller Albright
, is a term originally used to describe deposition of calcium
salts in the renal parenchyma
due to hyperparathyroidism
. It is now more commonly used to describe diffuse, fine, renal parenchymal calcification on radiology. During its early stages, nephrocalcinosis is visible on x-ray
, and appears as a fine granular mottling over the renal outlines. These outlines eventually come together to form a dense mass.
It is most commonly seen as an incidental finding with medullary sponge kidney
on an abdominal x-ray.
However, it may be severe enough to cause (as well as be caused by) renal tubular acidosis
or even end stage renal failure
, due to disruption of the renal tissue by the deposited calcium.
Stages of nephrocalcinosis
- Chemical nephrocalcinosis
- Microscopic nephrocalcinosis
- Macroscopic nephrocalcinosis
Causes of cortical nephrocalcinosis
Causes of medullary nephrocalcinosis
And other causes of hypercalcemia (and thus hypercalciuria)