Rife also claimed to have rendered such viruses and many others inert in the living patient by means of a "beam ray" device, which he claimed devitalized pathogens by inducing resonances in their constituent chemicals. The scientific community has concluded that Royal Rife's theory was flawed and his devices of no practical use, and newspaper articles have reported cases where cancer patients, some with potentially curable disease, have died while using Rife-type devices as alternatives to standard medical treatments.
Rife studied for six years with Hans Luckel, who was Carl Zeiss's optical scientist and researcher.
Rife married Mamie Ah Quinn in 1912 and she passed away in 1957. In 1960, Rife married Amelia Aragon. Rife died on August 5, 1971 in Grossmont Hospital, El Cajon, California, from a combination of valium and alcohol, at the age of 83.
On November 20, 1931, forty-four doctors attended a dinner advertised as "The End To All Diseases" at the Pasadena estate of Dr. Milbank Johnson. This dinner was honoring Dr. Arthur I. Kendall, professor at Northwestern Medical School, and developer of the "Kendall Medium" or "K-Medium," and Dr. Royal Rife, the developer of the "Rife microscope." Moving microorganisms from prepared, diseased human tissue were supposedly seen in Berkefeld-000 filtered form, still-photographed and motion pictured.
August, 1932, Science published a report by Dr. Edward C. Rosenow, M.D. (1875–1966). It said that, in addition to other viruses viewable with the standard lab microscope, small bodies were seen in the filtrate.
Rife's work was revived in the 1980s. An interest in Rife himself was revived by author Barry Lynes, who wrote a book about Rife entitled The Cancer Cure That Worked. The American Cancer Society described Lynes' claims as implausible, noting that the book is written "in a style typical of conspiratorial theorists."
In the late 1980s, Life Energy Resources mass-produced the REM SuperPro Generator. Three of the company's top distributors, Pat Ballistrea, Michael Ricotta, and Brian Strandberg, claimed it was based on Rife's devices and cured many diseases, including cancer and AIDS. They served prison time for selling unapproved medical devices and drugs as a result of their trials in 1993, 1994, and 1995. According to the Buffalo News, Judge Arcara told Ricotta: "Your sales strategy targeted the most vulnerable people, including those suffering from terminal disease ... It is especially cruel because, in many instances, it proved false hope to people who had no hope. Similarly, the American Cancer Society reported in 1994 that Rife machines were being sold in a "pyramid-like, multilevel marketing scheme" with the claim that the device was being suppressed by an establishment conspiracy against cancer "cures".
In Australia, the use of Rife's machine has been blamed for causing the deaths of cancer patients who could have been cured with conventional therapy.
The Attorneys General of Wisconsin and Minnesota sued Shelvie Rettmann, a proponent of Rife's "frequency generator" for deceptive trade practices and consumer fraud. The Court found that Rettmann had violated the law and that, as a result of her actions, a cancer patient had ceased chemotherapy and died four months later.
Although Rife devices are not registered by the U.S Food and Drug Administration and have been linked to deaths among cancer sufferers, the Seattle Times reported that over 300 people attended the 2006 Rife International Health Conference in Seattle, where dozens of unregistered devices were sold.