The Motisi Mafia family is a historical Mafia clan from the Pagliarelli area in Palermo. The Mafia roots of the family go back to the late 19th century. A Motisi was mentioned already in 1937 as the Mafia boss of Pagliarelli by Melchiorre Allegra, a mafioso physician who became an informant when he was arrested.
Matteo Motisi (Palermo, April 16, 1918 – September 5,2003) became a member of the Commission in 1983, as a result of the re-organization after the Second Mafia War. Previously, the Pagliarelli family had been part of the mandamento of Santa Maria di Gesù headed by Stefano Bontade.
Matteo Motisi was an ally of the Corleonesi and received life sentences for the murders of anti-mafia judges Rocco Chinnici, Giovanni Falcone and Paolo Borsellino as well as for 22 murders of members of the Bontade and Inzerillo clans during the Second Mafia War in 1981-83.
Giovanni Motisi (Palermo, January 1, 1959) succeeded his uncle Matteo Motisi as boss of the Pagliarelli family. He is a fugitive since 1993 and is considered to be one of the more powerful bosses of Palermo. He is considered to be close to Bernardo Provenzano. Motisi is on the "Most wanted list" of the Italian ministry of the Interior since 1998.