In enzymology, a monomethyl-sulfatase is an enzyme that catalyzes the chemical reaction

monomethyl sulfate + H2O rightleftharpoons methanol + sulfate

Thus, the two substrates of this enzyme are monomethyl sulfate and H2O, whereas its two products are methanol and sulfate.

This enzyme belongs to the family of hydrolases, specifically those acting on sulfuric ester bonds. The systematic name of this enzyme class is monomethyl-sulfate sulfohydrolase.


  • Ghisalba O, Kuenzi M "Biodegradation and utilization of monomethyl sulfate by specialized methylotrophs". Experientia. 39 1257–63.

External links

Gene Ontology (GO) codes

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