Metamucil is a bulk-producing laxative and fiber supplement manufactured by Procter & Gamble. The Metamucil brand has existed since 1934. The active ingredient is psyllium seed husks. It is often used to treat constipation, hemorrhoids, diverticular disease, and irritable bowel syndrome. It may also reduce cholesterol when taken daily. Metamucil is sold in powdered drink mixes, capsules, and wafers. Metamucil is available in several flavors, including Orange, Berry, and Pink Lemonade. A sugar-free version is also available.
- In Star Trek: The Next Generation Season One, an episode entitled "Skin of Evil" features a black tar-like creature named "Armus" who resides in a pool of the muck. In the special features on the DVD Jonathan Frakes who portrays Commander William T. Riker, discusses that the pool of muck was made from Metamucil and black printing ink.
- Gregg "Opie" Hughes and Jim Norton from the Opie and Anthony show on XM Satellite Radio - Channel 202 "The Virus" frequently use Metamucil. Norton has been quoted as saying: "Metamuce in the HOUSE!" Opie prefers the 'smooth texture' powder while Norton prefers the 'coarse milled'. Norton calls coarse milled "the fingernails of God scraping your colon clean."
- On the event of Senator John McCain cancelling his appearance (scheduled for September 24th, 2008) on "Late Night with David Letterman", Letterman took obvious offense. One of his remarks was directed at the changes in the Senator's behaviour due to a drop in poll numbers during the presidential election. Letterman announced that he used to admire McCain, but thought something "didn't smell right." "Someone put something in his Metamucil!", the host concluded.
- In Two and a Half Men Season Four, in episode entitled "Who's Vod Kanockers ?" Charlie jokes that sponsor of Aerosmith's tour is Metamucil.