Tabersonine 16-O-methyltransferase

S-adenosyl-L-methionine + 16-hydroxytabersonine $rightleftharpoons$ S-adenosyl-L-homocysteine + 16-methoxytabersonine

Thus, the two substrates of this enzyme are S-adenosyl methionine and 16-hydroxytabersonine, whereas its two products are S-adenosylhomocysteine and 16-methoxytabersonine.

This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:16-hydroxytabersonine 16-O-methyltransferase. Other names in common use include 11-demethyl-17-deacetylvindoline 11-methyltransferase, 11-O-demethyl-17-O-deacetylvindoline O-methyltransferase, S-adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline, and 11-O-methyltransferase. This enzyme participates in indole and ipecac alkaloid biosynthesis.

References

• Foucher AL, McIntosh A, Douce G, Wastling J, Tait A, Turner CM "A proteomic analysis of arsenical drug resistance in Trypanosoma brucei". Proteomics. 6 2726–32.
• Fahn W, Laussermair E, Deus-Neumann B and Stockigt J "Late enzymes of vindoline biosynthesis S-Adenosyl-L-methionine:11-O-demethyl-17-O-deacetylvindoline 11-O-methylase and unspecific acetylesterase". Plant Cell Rep. 4 337–340.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes