Le Nevez was born in Canberra, Australia in 1979 and attended The French-Australian School, Telopea High School and St Edmund's College, Canberra before accepted into NIDA aged 17. He graduated in 1999.
Le Nevez took a small role in an Australian made sci-fi series Farscape, followed by a part in teen drama Head Start. In 2002 he appeared in his first feature film Garage Days playing a drug-fulled rock star. He then played Aaron Reynolds, acomplice to the notorious Brenden James Abbott the "Post Card Bandit" in the TV miniseries of the same name.
The film Peaches saw him sharing a screen with Hugo Weaving and Jacqueline McKenzie, but it was the role in 2006 of notorious Mathew Wales (convicted of the murders of his mother Margaret Wales-King and step-father Paul King) in the TV movie The Society Murders that won Le Nevez critical acclaim. He won the Most Outstanding Actor on Australian television [Logie Award]] in 2006.
Le Nevez is currently filming The Tender Hook in Melbourne. Written and directed by Jonathan Ogilvie it is the story of Iris (Rose Byrne) and a love triangle that includes her roguish English lover, McHeath and Art (Matt Le Nevez), an earnest young boxer.