Mathrubhumi played important roles in many social reformation movements such as Vaikom Satyagraha and Guruvayur Satyagraha against untouchability. Participating in the Satyagraha, K.P. Keasava Menon was arrested and was sent to Jail. Patriots like P. Ramanunni Nair, K. Kelappan, P. Narayanan Nair, C.H. Kunjappa, K.A Damodara Menon, and A.P. Udayabhanu have served as Chief Editors of the newspaper.
In 1932 the company entered Magazine Journalism with the launch of Mathrubhumi Illustrated Weekly. In 1940, Viswaroopam, a comic magazine was launched with Sanjayan as the Chief Editor. Yugaprabhat, a bi-monthly in Hindi was also published whose editor was N. V. Krishna Warrier. But now, these two publications are not in print.
Mathrubhumi is the second most circulated newspaper in Kerala. Inside Kerala, it is published from Calicut, Thiruvananthapuram, Kottayam, Ernakulam, Thrissur, Kannur, Palakkad, Malappuram, and Kollam. Outside Kerala, it is published from Chennai, Bangalore, Mumbai, and New Delhi. It has a circulation of over 1.3 million and its readership is around 7.5 million.
Currently, M.P. Veerendra Kumar is the Chairman and Managing Director of Mathrubhumi.
The Editors Guild of India has strongly condemned threats to the editor of Mathrubhumi daily, by leaders of the CPI(M) and its frontal organisations in Kerala.