The street connects Rainford Gardens (off Whitechapel) to North John Street, and is located in an area of the city centre known today as "The Cavern Quarter". Historically it was the centre of Liverpool's wholesale fruit and vegetable market. Mathew Street is visited by thousands of tourists a year, who visit the Cavern Club and many surrounding attractions including a statue of John Lennon, a Beatles store and several pubs formerly frequented by The Beatles. A wall in Mathew Street is adorned by a sculpture entitled "Four Lads Who Shook the World".
It was also home to the influential music club Eric's, which played host to many famous punk bands from its opening in 1976, despite only being open for 4 years.