| Representative
| Party
| Years
| District home
| Notes |
| District created
| 1795 |
| Benjamin Goodhue
| Federalist
| March 41795 – June 111796
|
| Redistricted from the , resigned after election to US Senate |
| Vacant
| June 111796 - December 71796 |
| Samuel Sewall
| Federalist
| December 71796 – January 101800
|
| resigned |
| Vacant
| January 101800 - November 251800 |
| Nathan Read
| Federalist
| November 251800 – March 31803
|
| |
| Seth Hastings
| Federalist
| March 41803 – March 31807
|
| Redistricted from the |
| Jabez Upham
| Federalist
| March 41807 - 1810
| Brookfield
| Resigned |
| Vacant
| 1810 - October 81810 |
| Joseph Allen
| Federalist
| October 81810 - March 31811
| Worcester
| Retired |
| Elijah Brigham
| Federalist
| March 41811 – March 31815
|
| Redistricted to the |
| Laban Wheaton
| Federalist
| March 41815 – March 31817
|
| Redistricted from the |
| Marcus Morton
| Democratic-Republican
| March 41817 – March 31821
| Taunton
| |
| Francis Baylies
| Federalist
| March 41821 – March 31823
|
| Redistricted to the |
| Vacant
| March 31823 - December 131824 |
| John Bailey
| Adams–Clay Democratic-Republican
| December 131824 – March 31825
|
| contested election with state, eventually seated |
| Adams
| March 41825 – March 31829
|
|
| Anti-Jackson
| March 41829 – March 31831
| |
| Henry A. S. Dearborn
| Anti-Jackson
| March 41831 – March 31833
|
| |
| William Baylies
| Anti-Jackson
| March 41833 – March 31835
|
| |
| Nathaniel B. Borden
| Jacksonian
| March 41835 – March 31837
|
|
|
| Democratic
| March 41837 – March 31839
| |
| Henry Williams
| Democratic
| March 41839 – March 31841
|
| |
| Nathaniel B. Borden
| Democratic
| March 41841 – March 31843
|
| |
| Barker Burnell
| Whig
| March 41843 – June 151843
|
| Redistricted from the , died |
| Vacant
| June 151843 - December 71843 |
| Joseph Grinnell
| Whig
| December 71843 – March 31851
|
| |
| Zeno Scudder
| Whig
| March 4, 1851 – March 3, 1853
|
| Redistricted to the |
| Edward Dickinson
| Whig
| March 4, 1853 - March 3, 1855
| Amherst
| |
| Calvin C. Chaffee
| Know Nothing
| March 41855 – March 31857
|
|
|
| Republican
| March 41857 – March 31859
| |
| Charles Delano
| Republican
| March 41859 – March 31863
|
| |
| Henry L. Dawes
| Republican
| March 31863 – March 31873
|
| Redistricted from the , Redistricted to the |
| Alvah Crocker
| Republican
| March 4, 1873 - December 26, 1874
| Fitchburg
| Redistricted from the , Died |
| Vacant
| December 26 1874 - January 27 1875 |
| Charles A. Stevens
| Republican
| January 27 1875 - March 3, 1875
|
| |
| Julius H. Seelye
| Independent
| March 41875 – March 31877
|
| |
| Amasa Norcross
| Republican
| March 41877 – March 31883
|
| |
| William W. Rice
| Republican
| March 41883 – March 31887
|
| Redistricted from the |
| John E. Russell
| Democratic
| March 41887 – March 31889
|
| |
| Joseph H. Walker
| Republican
| March 41889 - March 3, 1893
|
| Redistricted to the |
| Michael J. McEttrick
| Independent Democrat
| March 41893 – March 31895
|
| |
| Harrison H. Atwood
| Republican
| March 41895 - March 31897
| Boston
| Lost Renomination |
| Samuel J. Barrows
| Republican
| March 41897 – March 31899
|
| |
| Henry F. Naphen
| Democratic
| March 41899 – March 31903
|
| |
| William S. McNary
| Democratic
| March 41903 – March 31907
|
| |
| Joseph F. O'Connell
| Democratic
| March 41907 – March 41911
|
| |
| William Francis Murray
| Democratic
| March 41911 – September 281914
|
| resigned to become Postmaster of Boston |
| Vacant
| September 281914 - March 41915 |
| Peter Tague
| Democratic
| March 4, 1915 – March 3, 1919
|
| |
| John F. Fitzgerald
| Democratic
| March 4, 1919 – October 23, 1919
|
| |
| Peter Tague
| Democratic
| October 23, 1919 – March 3, 1925
|
| successfully contested Fitzgerald's election |
| John J. Douglass
| Democratic
| March 4, 1925 – March 3, 1933
|
| Redistricted to the |
| George H. Tinkham
| Republican
| March 4, 1933 – January 3, 1943
|
| Redistricted from the |
| Christian Herter
| Republican
| January 3, 1943 – January 3, 1953
|
| Retired to become Governor |
| Laurence Curtis
| Republican
| January 3, 1953 – January 3, 1963
| Boston
| Retired to run (unsuccessfully) for U.S. Senate |
| Joseph William Martin, Jr.
| Republican
| January 3, 1963 – January 3, 1967
| North Attleborough
| Redistricted from the Lost renomination |
| Margaret M. Heckler
| Republican
| January 3, 1967 – January 3, 1983
| Wellesley
| Redistricted to the and lost reelection to the 4th's incumbent |
| Gerry E. Studds
| Democratic
| January 3, 1983 – January 3, 1997
|
| Redistricted from the Retired |
| Bill Delahunt
| Democratic
| January 3, 1997 – present
| Quincy
| Incumbent |
Prior to the 1992 remapping, the district covered areas southwest of Boston which are now in the and districts.