Marchiafava-Bignami disease

Marchiafava-Bignami disease

Marchiafava-Bignami disease is a progressive neurological disease characterized by corpus callosum demyelination and necrosis and subsequent atrophy.

Eponym

It was first described in 1903 by the Italian pathologists Amico Bignami and Ettore Marchiafava in an Italian Chianti drinker.

Causes

It is classically associated with chronic alcoholics.

References

External links

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