Mangostin is a natural organic compound isolated from various parts of the mangosteen tree (Garcinia mangostana). It is a yellow crystalline solid with a xanthone core structure. Mangostin and a variety of other xanthones from mangosteen have been investigated for biological properties including antioxidant, anti-bacterial, anti-inflammatory, and anticancer activities.
The rind of partially ripe mangosteen fruit yields mangostin, also β-mangostin. That of fully ripe fruits contains the xanthones gartanin, 8-disoxygartanin, and normangostin. A derivative of mangostin, mangostin-3,6-di-O-glucoside, is a central nervous system depressant and causes a rise in blood pressure.