On the Rocky Horror Picture Show DVD commentary with Richard O'Brien (Riff-Raff) and Patricia Quinn (Magenta), O'Brien confessed being extremely nervous during the opening of the Rocky Horror Show. However, when the chorus of Over at the Frankenstein Place was sung, he could hear the audience laughing, and was much less nervous.
The song has been covered by The Alkaline Trio for the Rocky Horror Punk Show Album featuring Various Artists.
This was one of the songs sung by O'Brien as he revisited Oakley Court (the castle's location) for VH1's Behind The Music special. O'Brien sings Janet's verse before describing how the song was, and how the camera would pan up to a 'very handsome chap', then O'Brien proceeded to sing his verse. O'Brien also sung the song in an acoustic style as an extra for the Rocky Horror Interactive Show PC Game.
In the 2000 revival for Broadway, it was performed by Alice Ripley, Jarrod Emick, and Raul Esparza. Despite the revival's penchant for being like the film version when it came to the lyrics and titles of the songs, Brad's verse is intact.