Recent DNA studies have split this genus into two clades. The first includes M. procera, M. mastoidea, M. clelandii and closely related species, while the second clade is more diverse and includes M. rhacodes, Chlorophyllum molybdites and many others.
The generic status of Macrolepiota is not unanimously held as some current books still leave the members of Macrolepiota in Lepiota.