Lanthanum hexaboride (LaB₆, also called lanthanum boride and LaB) is an inorganic chemical, a boride of lanthanum. It is a refractory ceramic material that has a melting point of 2210 °C, is insoluble in water and hydrochloric acid. It has a low work function and one of the highest electron emissivities known, and is stable in vacuum. Its CAS number is . Stoichiometric samples are colored intense purple-violet, while boron-rich ones (above LaB_6.07) are blue. Ion bombardment changes its color from purple to emerald green.

The principial use of lanthanum hexaboride is in hot cathodes, either as a single crystal or as a coating deposited by physical vapor deposition. Hexaborides, such as Lanthanum hexaboride (LaB₆) and cerium hexaboride (CeB₆), have low work functions, around 2.5 eV. They are also somewhat resistant to cathode poisoning. Cerium hexaboride cathodes have a lower evaporation rate at 1700 K than lanthanum hexaboride, but they becomes equal at temperatures above 1850 K. Cerium hexaboride cathodes have one and half the lifetime of lanthanum hexaboride, due to the former's higher resistance to carbon contamination. Hexaboride cathodes are about ten times "brighter" than tungsten cathodes, and have 10-15 times longer lifetime. They are used eg. in electron microscopes, microwave tubes, electron lithography, electron beam welding, X-Ray tubes, and free electron lasers.

Lanthanum hexaboride slowly evaporates from the heated cathodes and forms deposits on the Wehnelt cylinders and apertures.