The Kowalski ester homologation
is a chemical reaction
for the homologation
This reaction was designed as a safer alternative to the Arndt-Eistert synthesis. The Kowalski reaction is named after its inventor, Conrad J. Kowalski.
The mechanism is disputed.
A modification of the procedure has been described that results in higher yields.
By changing the reagent in the second step of the reaction, the Kowalski ester homologation can also be used for the preparation of silyl ynol ethers.