Five years later the birth of his severely brain-damaged son marked a turning point in his life and work. His best known novel, A Personal Matter (1964, tr. 1968), deals with a father's slow acceptance of his similarly handicapped infant son. Several of his other works concern this theme. In life, he and his wife have devoted much of their lives to their son's care.
Oe's other works include more than 20 novels, among them The Silent Cry (1967, tr. 1974), The Pinch Runner Memorandum (1976, tr. 1993), and A Quiet Life (1990, tr. 1996), several short-story collections, essays, and Hiroshima Notes (1965, tr. 1995), which chronicles the courage of the victims of the nuclear attack. His often angry and politically charged tales, his recurrent themes of abnormality, sexuality, and marginality, and his gritty, realistic style set him apart from the mainstream Japanese literary tradition. Oe was awarded the Nobel Prize in Literature in 1994. Somersault (2003), his first novel since winning the prize, revolves around a terrorist religious cult and its charismatic leader.
His firstborn son, Hikari Oe, 1963-, although initially uncommunicative and still only minimally functional, developed impressive musical abilities and has become an accomplished composer.