In 1971 she recorded with St Winifreds Choir on the school's first album of modern hymns. In 1977 she played in punk group Blackout alongside Tony Ogden and Gordon King. She joined the group Illustration in 1979 and recorded material with Martin Hannett as producer for Some Bizzare Records.
In 1986 she formed the Manchester group What? Noise with her husband Chris Nagle and was signed to One Little Indian Records, where she contributed to the album Fat and the EP Vein. What?Noise material was also featured on compilation albums for various record companies.
Adamson was a member of The Fall between 1995-2001, playing keyboards, guitar and computers. She contributed to The Light User Syndrome, Levitate, The Marshall Suite and The Unutterable. Writing credits include the singles "The Masquerade" and "Touch Sensitive", later used in an advert for Vauxhall Corsa cars (2003-2006).
A large VAT invoice was given to The Fall in 1997. Incurred before Adamson joined, it caused tensions with the members it had been issued to and led to a split in the group in 1998. The group reformed with frontman Mark E. Smith, Adamson, and new musicians.
Since 2001 Adamson has continued to write and perform under the name Invisiblegirl and released single Fun in September 2006. Invisiblegirl has now expanded into Invisiblegirl Music Publishing and Invisiblegirl Records.