Isomescaline, or 2,3,4-trimethoxyphenethylamine, is a lesser-known psychedelic drug. It is an isomer of mescaline, as well as an analog of TIM-2, TIM-3, and TIM-4. Isomescaline was first synthesized by Alexander Shulgin. In his book PiHKAL (Phenethylamines i Have Known And Loved), the minimum dosage is listed as 400 mg, and the duration unknown. Despite its structural similarity to mescaline, isomescaline produces no effects. Very little data exists about the pharmacological properties, metabolism, and toxicity of isomescaline.