Inosine nucleosidase

Inosine nucleosidase

In enzymology, an inosine nucleosidase is an enzyme that catalyzes the chemical reaction

inosine + H2O rightleftharpoons D-ribose + hypoxanthine

Thus, the two substrates of this enzyme are inosine and H2O, whereas its two products are D-ribose and hypoxanthine.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is inosine ribohydrolase. Other names in common use include inosinase, and inosine-guanosine nucleosidase. This enzyme participates in purine metabolism.

References

  • KOCH AL "Some enzymes of nucleoside metabolism of Escherichia coli". J. Biol. Chem. 223 535–49.
  • Tarr HLA "Fish muscle riboside hydrolases". Biochem. J. 59 386–391.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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