Hydroxylysine kinase&o=10616

Hydroxylysine kinase

In enzymology, a hydroxylysine kinase is an enzyme that catalyzes the chemical reaction

GTP + 5-hydroxy-L-lysine rightleftharpoons GDP + 5-phosphonooxy-L-lysine

Thus, the two substrates of this enzyme are GTP and 5-hydroxy-L-lysine, whereas its two products are GDP and 5-phosphonooxy-L-lysine.

This enzyme belongs to the family of transferases, specifically those transferring phosphorus-containing groups (phosphotransferases) with an alcohol group as acceptor. The systematic name of this enzyme class is GTP:5-hydroxy-L-lysine O-phosphotransferase. Other names in common use include hydroxylysine kinase (phosphorylating), and guanosine triphosphate:5-hydroxy-L-lysine O-phosphotransferase. This enzyme participates in lysine degradation.

References

  • Hiles RA, Henderson LM "The partial purification and properties of hydroxylysine kinase from rat liver". J. Biol. Chem. 247 646–51.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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