Hydroxylamine reductase (NADH)

NH₃ + NAD⁺ + H₂O $rightleftharpoons$ hydroxylamine + NADH + H⁺

The 3 substrates of this enzyme are NH₃, NAD⁺, and H₂O, whereas its 3 products are hydroxylamine, NADH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is ammonium:NAD+ oxidoreductase. Other names in common use include hydroxylamine reductase, ammonium dehydrogenase, NADH-hydroxylamine reductase, N-hydroxy amine reductase, hydroxylamine reductase (NADH2), and NADH2:hydroxylamine oxidoreductase. This enzyme participates in nitrogen metabolism.

References

• Bernheim ML "The hydroxylamine reductase of mitochondria". Arch. Biochem. Biophys. 134 408–13.
• Bernheim ML, Hochstein P "Reduction of hydroxylamine by rat liver mitochondria". Arch. Biochem. Biophys. 124 436–42.
• Wang R and Nicholas DJD "Some properties of nitrite and hydroxylamine reductases from Derxia gummosa". Phytochemistry 25 2463–2469.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes