Hydroxylamine oxidase

hydroxylamine + O₂ $rightleftharpoons$ nitrite + H₂O

Thus, the two substrates of this enzyme are hydroxylamine and O₂, whereas its two products are nitrite and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with oxygen as acceptor. The systematic name of this enzyme class is hydroxylamine:oxygen oxidoreductase. Other names in common use include HAO and hydroxylamine oxidoreductase. This enzyme participates in nitrogen metabolism. It employs one cofactor, heme.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code .

References

• Hooper AB, Balny C "Reaction of oxygen with hydroxylamine oxidoreductase of Nitrosomonas: fast kinetics". FEBS. Lett. 144 299–303.
• Lipscomb JD, Hooper AB "Resolution of multiple heme centers of hydroxylamine oxidoreductase from Nitrosomonas. 1. Electron paramagnetic resonance spectroscopy". Biochemistry. 21 3965–72.
• Rees MK "Studies of the hydroxylamine metabolism of Nitrosomonas europaea. I Purification of hydroxylamine oxidase". Biochemistry. 7 353–66.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes