The 1,765,000 square foot (164,000 m²) building contains 65,000 cubic yards (50,000 m³) of concrete and 12,000 tons of structural steel. It took about 2,700 truckloads to excavate the building's foundation, and 1,300,000 man hours over nearly two years to finish. 28 high speed elevators serve Hyatt Center.
The building features extensive landscaping both inside and outside from bamboo groves, complete with fountains, lining the modern lobby to lush green grass in raised curved stone planters that surround the building. The Hyatt Center also contains art panels by Keith Tyson and a trompe l'oeil mural by Ricci Albenda.
The anchor tenant of the building is Mayer Brown LLP, which occupies floors 32-45 and shares the floor 2 cafe with a few of the other tenants.