HES5 regulates brain development process. HES5 expression significantly higher in squamous cervical carcinoma than in CIN as well as higher in CIN than normal cervical epithelia. Human HES5 gene binds to Notch receptor and expression of HES5 decreases during cartilage differentiation.
Hey2 functions in parallel with Hes1 and Hes5 for mammalian auditory sensory organ development.(Research article)
Feb 26, 2008; Authors: Shuangding Li ; Sharayne Mark ; Kristen Radde-Gallwitz ; Rebecca Schlisner ; Michael T Chin ; Ping Chen...