According to Gaudiya tradition it was during this time that Gopala Bhatta had a spiritual vision in which Chaitanya Mahaprabhu revealed Himself as an avatar of Krishna, the Supreme God of Gaudiya Vaishnavism. In the vision Krishna then told him that in the town of Vrindavan he would meet with two devotees, namely Rupa Goswami and Sanatana Goswami who would instruct him in the finer details of devotional service (bhakti).
When Gopala Bhatta awoke from the experience, he wanted to leave for Vrindavan at once, however Chaitanya Mahaprabhu told him to stay and serve his parents. After Chaitanya's departure, Gopal Bhatta took guidance from his uncle Prabhodananda Sarasvati. Gopal Bhatta took care of his parents into their old age, and then after they died he then traveled to Vrindavana. There he met Rupa and Sanatana who accepted him as a brother. Gopal Bhatta later helped Santana compile the book Hari Bhakti Vilasa.
When Chaitanya discovered that Gopala Bhatta was in Vrindavan, he was extremely pleased and sent some of his personal belongings to Gopala Bhatta, who worshiped them. Mahaprabhu also sent a letter instructing Gopala Bhatta to help Rupa and Sanatana compile Vaishnava literature. Gopala Bhatta accepted this instruction as his life and soul, and he later also engaged his disciple Srinivasa Acarya in carrying the writings to Bengal.