• Mouth
• Whoopie pie, a type of dessert food
• Gob (band), a punk band from Vancouver, BC, Canada
• Gob, the king of the gnomes in folklore
• Gob or boney piles, low-coal-content waste from coal mining operations
• Gob, a cylinder of molten glass used in the Glass Container Industry
• Gob (mining), a cavity behind a longwall (See Longwall mining.)

GOB as an acronym may refer to:

• GObject Builder, an object preprocessor for GObject/C
• George Oscar "G.O.B." Bluth II, a fictional character on the TV show Arrested Development
• Gobowen railway station, England, by National Rail station code
• Grand Orient of Belgium