glyoxylate + CoA + NADP⁺ $rightleftharpoons$ oxalyl-CoA + NADPH + H⁺

The 3 substrates of this enzyme are glyoxylate, CoA, and NADP⁺, whereas its 3 products are oxalyl-CoA, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is glyoxylate:NADP+ oxidoreductase (CoA-oxalylating). This enzyme participates in glyoxylate and dicarboxylate metabolism.

References

• Quayle JR and Taylor GA "Carbon assimilation by Pseudomonas oxalaticus (OX1). 5. Purification and properties of glyoxylic dehydrogenase". Biochem. J. 78 611–615.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes