Glycoprotein IIB/IIIA inhibitor

Glycoprotein IIb/IIIa

In medicine, glycoprotein IIb/IIIa, also gpIIb/IIIa, is an integrin found on platelets. Calcium-dependent association of gpIIb and gpIIIa is required for normal platelet aggregation and endothelial adherence.

Pathology

Defects in glycoprotein IIb/IIIa causes Glanzmann's thrombasthenia.

Medicine

Glycoprotein IIb/IIIa inhibitors can be used to prevent blood clots in an effort to decrease the risk of heart attack or stroke.

See also

References

External links

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