a glycerophosphodiester + H₂O $rightleftharpoons$ an alcohol + sn-glycerol 3-phosphate

Thus, the two substrates of this enzyme are glycerophosphodiester and H₂O, whereas its two products are alcohol and sn-glycerol 3-phosphate.

This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric diester bonds. The systematic name of this enzyme class is glycerophosphodiester glycerophosphohydrolase. Other names in common use include gene hpd protein, glycerophosphoryl diester phosphodiesterase, and IgD-binding protein D. This enzyme participates in glycerophospholipid metabolism.

Structural studies

As of late 2007, 9 structures have been solved for this class of enzymes, with PDB accession codes , , , , , , , , and .

References

• Larson TJ, Ehrmann M, Boos W "Periplasmic glycerophosphodiester phosphodiesterase of Escherichia coli, a new enzyme of the glp regulon". J. Biol. Chem. 258 5428–32.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes