, a gluconate 2-dehydrogenase (acceptor)
is an enzyme
the chemical reaction
- D-gluconate + acceptor 2-dehydro-D-gluconate + reduced acceptor
Thus, the two substrates of this enzyme are D-gluconate and acceptor, whereas its two products are 2-dehydro-D-gluconate and reduced acceptor.
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with other acceptors. The systematic name of this enzyme class is D-gluconate:acceptor 2-oxidoreductase. Other names in common use include gluconate oxidase, gluconate dehydrogenase, gluconic dehydrogenase, D-gluconate dehydrogenase, gluconic acid dehydrogenase, 2-ketogluconate reductase, D-gluconate dehydrogenase, 2-keto-D-gluconate-yielding, and D-gluconate:(acceptor) 2-oxidoreductase. This enzyme participates in pentose phosphate pathway. It employs one cofactor, FAD.
- Matsushita K, Shinagawa E, Ameyama M "D-Gluconate dehydrogenase from bacteria, 2-keto-D-gluconate-yielding, membrane-bound". Methods. Enzymol. 89 Pt D 187–93.
- Ramakrishnan T and Campbell JJR "Gluconic dehydrogenase of Pseudomonas aeruginosa". Biochim. Biophys. Acta 17 122–127.
- The CAS registry number for this enzyme class is .