Gepps Cross is best known for the five-way intersection with Grand Junction Road going east and west, Main North Road south and north east, and Port Wakefield Road going North. The intersection is not grade-separated. It is controlled by traffic lights, and all five roads have at least three lanes in each direction. These roads include the main highways from Adelaide to Western Australia and the Northern Territory (via Port Wakefield Road), New South Wales (via Main North Road), the northern suburbs of Adelaide and the northern parts of South Australia (both roads). Port Adelaide is to the west, and the major freight hubs are northwest of Gepps Cross. A major route from Port Adelaide towards Victoria and the South and east of South Australia is east along Grand Junction Road then south along Portrush Road to the South Eastern Freeway.