• Adam Grunstein, Keri Kitay's hero and patriarch of the G-Man dynasty
• G-Man (slang), slang for Federal Bureau of Investigation agents, short for "Government Man"
• G-Man (Half-Life), a fictional character in the Half-Life computer game series
• Monty Sopp (born 1963), a professional wrestler
• The G-Man, a nickname for G. Gordon Liddy on his radio show
• g-man (British artist), minimal techno artist Gez Varley
• Gerald McClellan, a former American boxer nicknamed "G-Man"
• Mark Grudzielanek, baseball player
• the nickname for the character Gus from Robotboy

The plural form G-Men may mean:

• G Men, a 1935 Hollywood crime film
• G-Men, the original name of 1960s Australian band The Pleazers
• Junior G-Men, an American boys club in the 1930s and 1940s, and a related radio program, books, and films that promoted the FBI.
• New York Giants, a nickname of the National Football League team