Fumarate reductase (NADH)

Fumarate reductase (NADH)

In enzymology, a fumarate reductase (NADH) is an enzyme that catalyzes the chemical reaction

succinate + NAD+ rightleftharpoons fumarate + NADH + H+

Thus, the two substrates of this enzyme are succinate and NAD+, whereas its 3 products are fumarate, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is succinate:NAD+ oxidoreductase. Other names in common use include NADH-fumarate reductase, NADH-dependent fumarate reductase, and fumarate reductase (NADH).

References

  • Hopgood MF and Walker DJ "Succinic acid production by rumen bacteria. III. Enzymic studies on the formation of succinate by Ruminococcus flavefaciens". Aust. J. Biol. Sci. 22 1413–1424.

External links

The CAS registry number for this enzyme class is .

Gene Ontology (GO) codes

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