Fumarase

Fumarase (or fumarate hydratase) is an enzyme involved in the Krebs Cycle (aka the Tricarboxylic Acid Cycle aka the Citric Acid Cycle) that catalyzes the hydration (addition of H₂O across a double bond) of Fumarate to L-malate (See the entry on optical isomer).

Fumarate + H2O <-> L Malate

Biochemical Pathway

• Diagram TCA Cycle at KEGG, gives some details on the TCA cycle in which fumerase acts. [Fumarase is labeled '4.2.1.2' in the lower left hand corner of this diagram.
• structure of Fumarate
• Structure of L Malate
• See also Citric Acid Cycle on Wikipedia.

See also

• Fumarase deficiency

External links

• Crystal structure of Yeast Fumarase at the Protein Data Bank.