A

• Alfonso of Molina (1203–1272), second son of King Alfonso IX of Leon
• Alfonso Quiñónez Molina (1874–1950), President of El Salvador twice 1918–1927
• Alfred Molina (1953—), English actor
• Alvaro de Molina (1957—), American banker, chief financial officer of Bank of America Corporation
• Ángela Molina (1955—), Spanish actress
• Antonio Muñoz Molina (1956—), Spanish writer and member of the Royal Spanish Academy
• Antonio Sebastián de Toledo, marqués de Mancera (1625–[?]), viceroy of New Spain 1664–1673
• Antonio Tejero Molina (1932—), a Spanish Lieutenant-Colonel who attempted a coup d'état
• Arturo Armando Molina (1927—), President of El Salvador 1972–1977

B

• Bengie Molina (1974—), Puerto Rican professional baseball player
• Benigno Molina Soto (1974—), Singer and composer of Mexican music, "ramchero" y "boleros"

D

• Dafne Molina (1982—), Mexican beauty queen

E

• Enrique Molina (1944—), Cuban actor
• Enrique Molina Sobrino (contemporary), wealthy Mexican businessman, sued for fraud by the Mexican government
• Enrique Molina Vargas (1968—), Spanish middle-distance runer

F

• Florencio Molina Campos (1891–1959), Argentine painter
• Fray Alonzo de Molina (dates unknown), author of a classic Nahuatl-Spanish Vocabulario

G

• Gerardo Molina (1906–1991), Colombian writer, politician, and academic
• Gloria Molina (contemporary), American politician, chairwoman of the Los Angeles County Board of Supervisors

H

• Hector Garcia-Molina (contemporary), American engineering professor, member of the Board of Directors of Oracle Corporation
• Hilda Molina (contemporary), Cuban neurosurgeon and dissident
• Hugo Antonio Laviada Molina, a Mexican politician

I

• Infanta Maria Francisca, Countess of Molina (1800–1834), Portuguese infanta daughter of King John VI of Portugal
• Infante Carlos, Count of Molina (1788–1855), son of King Charles IV of Spain, Carlist pretender to the throne of Spain

J

• Jacinto Molina (Paul Naschy) (1934—), Spanish movie actor, screenwriter, and director
• John John Molina (Juan Molina) (1965—), Puerto Rican boxer
• Jason Molina (contemporary), American indie rock musician
• Jorge Molina (1966—), Cuban film director
• José Angel Molina (1958—), Puerto Rican boxer
• José Antonio Molina Rosito (1926&mdash), Honduran botanist (Ant.Molina)
• José Molina (1975—), Puerto Rican professional baseball player
• José Domingo Molina Gómez (1896–1969), interim President of Argentina 1955
• José Francisco Molina (1970—), Spanish football player
• Juan Francisco de Molina (19th c.), President of Honduras 1839
• Juan Ignacio Molina (1740–1829), Chilean priest and naturalist
• Juan Manuel Molina (1979—), Spanish race walker
• Juana Molina (1962—), Argentine singer, songwriter, and actress
• Justo Páez Molina (1902–1969), Argentine politician, Governor of Córdoba 1963–1966

L

• Laura Molina (contemporary), Spanish badminton player
• Luis Molina (1535–1600), Spanish Jesuit and professor

M

• Manuel Luis Quezon y Molina (1877–1944), first or second president of the Philippines
• Mario J. Molina (1943—), Mexican Nobel Prize recipient in chemistry
• Marquis de Molina (19th c.), Spanish politician and government minister

O

• Olivia Molina (1946—), German-Mexican singer

R

• Rafael Leónidas Trujillo Molina (1891–1961), dictator of the Dominican Republic 1930–1961
• Rafael Molina Sánchez (1841–1900), Spanish matador
• Ralph Molina (contemporary), American rock drummer
• Raúl De Molina (1959—), Cuban television celebrity on Univision
• Remigio Molina (1970—), Argentine Olympic boxer
• Rolando Molina (1971—), El Salvadoran-American actor

S

• Scott Molina (1960—), American championship triathlete

T

• Tirso de Molina (1571–1648), Spanish dramatist and poet

Y

• Yadier Molina (1982—), Puerto Rican professional baseball player