• Abraham Emanuel Fröhlich, German evangelist, theologian and writer
• Albrecht Fröhlich, German Jewish mathematician
• Fröhlich Prize, prize of the London Mathematical Society, in memory of Albrecht Fröhlich
• Edward Fröhlich Haskell, scientist and philosopher
• Eric Froehlich, an American professional poker player
• Gustav Fröhlich, a German actor
• Harold E. Froehlich (1923-2007), American engineer who designed deep-diving exploratory submarine
• Harold Vernon Froehlich, U.S. Congressman from Wisconsin, 1973-1975
• Herbert Fröhlich (1905 - 1991), German-born British physicist.
• Jack Froehlich, American rocket scientist
• Froelich (crater) (only one h) crater on the moon named after Jack
• Jean-Pierre Frohlich, New York City Ballet balletmaster and former soloist
• Katharina Fröhlich (1801-1879), German lover of the poet Franz Grillparzer
• Paul Frölich, German politician
• Paul Froehlich, Illinois politician
• Péter Fröhlich, Hungarian fencing master and Olympic coach
• Peter Gay (born Peter Joachim Fröhlich)
• Samuel Heinrich Froehlich (1803-1857), evangelist

See also

• Fröhlicher spectral sequence, a mathematical tool in the theory of complex manifolds
• Babinski-Fröhlich syndrome or Frölich's syndrome, another name for Adiposogenital Dystrophy
• Phyllis Frelich, American actress
• Dunkelfelder, a grape variety also known as Farbtraube Froelich or Froelich V 4-4 after the grape breeder Gustav Adolf Froelich (1847-1912).