The album contained tracks from the Powderfinger's first four albums, as well as two previously unreleased songs, "Bless My Soul" and "Process This". "Bless My Soul" was also released as a single.
MTV Scene writer Craig Tangsley also commented on fears about the "death" of the band, stating that he spoke to Bernard Fanning about the band's death as "it's inevitable to talk when someone releases a best of album". Fanning denied that the band was finished, instead claiming that Fingerprints: The Best of Powderfinger, 1994-2000 was spawned due to a deal with the band's record label. He also assured readers that the band had another album planned.
Ciao reviewer cocoklo agreed with Universal's assessment, stating that "If there ever was a band, in my opinion, that needed a greatest hits album, it's Powderfinger". However, he noted another issue which had some influence on the production of the album - the issue of which songs to include. As the band had only released five albums, they were forced to mostly include the singles they had previously released.
Throughout production stages, the album was not referred to as Fingerprints: The Best of Powderfinger, 1994 - 2000, but rather by its alternative title; From Heavy Metal to Centenary Medal. It is unknown when the band decided on the final title of the album.
Soulshine reviewer Dave Hardwick gave the album three stars, stating that "the cynic in me can't help asking whether that is the point"; alluding to the overbearing presence of industry politics regarding the release of a Best Of collection, and complaining of a lack of surprises in the choice of tracks. However, he agreed that the album was a good starting point for "those new to the band".
Ciao reviewer cocoklo rated the album positively. The new songs on the album were praised, with the comment "both of which are stunning", and stating that none of the songs were disappointing. The review highly recommended the album, and again stated that it was an excellent introduction to the band. Fasterlouder.com.au commentator Elissa said the album contained an excellent selection of songs that represented "essence of the band from its signature melodies", and said that "Bless My Soul" was set "to become a Powderfinger favourite".