• FAB, the IATA airport code for Farnborough Airfield
• Federated Array of Bricks, a low-cost distributed storage system that provides block-level storage and uses distributed data replication for fault tolerance
• Feline Advisory Bureau, a UK feline charity
• Flavoured Alcoholic Beverages, also known as alcopops
• Força Aérea Brasileira, the Brazilian Air Force
• Fugasnaya aviatsionnaya bomba ('Aviation Demolition Bomb'), the term for Russian general purpose bombs
• Film Advisory Board
• Federation de l'Automobile de Belarus, a member of the FIA
• Feminist Approaches to Bioethics
• Functional Airspace Block

Fab may mean:

• Fab (brand), a frozen confectionery
• Fab (detergent), marketed by Colgate-Palmolive

In science and technology:

• Fab region, the fragment antigen binding portion of an antibody
• Fab (semiconductors), a fabrication plant for semiconductor manufacture
• Fabber, a desktop multipurpose factory, ideally self-replicating
• Fast atom bombardment, a mass spectrometry technique in chemistry
• The French-American-British classification systems for hematological disease
• Fuel air bomb, an explosive device based on the ignition of an aerosolized fuel cloud

In culture:

• F.A.B., a radio sign-off used in the Thunderbirds TV series
• Fab (magazine), a Canadian gay magazine
• Fab (book) by Neil Gershenfeld
• Fab (nightclub), a gay nightclub located in Manila, Philippines
• Fabrice Morvan, singer of Milli Vanilli
• Fabrizio Moretti, drummer in The Strokes