Blondin-Andrew is a Dene who was the Member of Parliament for the district of Western Arctic in the Northwest Territories. She was also Minister of State (Northern Development) in the Liberal Cabinet of Prime Minister Paul Martin.
She was the first Aboriginal woman to be elected to the Parliament of Canada. She was first elected in the 1988 election. Before embarking upon her political career, she spent many years working in the North as a teacher, and later as an Assistant Deputy Minister with the territorial government. Under Prime Ministers Chrétien and Martin, she served as Secretary of State then Minister of State, respectively, for Children and Youth.