See R. W. Corrigan, Masterpieces of the Modern Italian Theater (1967).
Born in Naples, De Filippo began acting at the age of 5 and in 1932 formed a theater company with his brother Peppino and sister Titina. Peppino left the troupe in 1944 and Titina departed by the early 1950s. Eduardo starred in De Sica's L'oro di Napoli with Totò and Sophia Loren in 1954. His translation of Shakespeare's The Tempest into Neapolitan was published in 1982.
On 15 December 2007, BBC Radio 4 broadcast his 1959 play "Saturday, Sunday and Monday" (Sabato, domenica e lunedì) in English.
In 1981, De Filippo was appointed life senator of the Italian Republic. He died in Rome.