Samuel Edwin Weir (March 14, 1903, Superior, Nebraska – May 15, 1991) was the first Nebraska Cornhusker football player elected to the College Football Hall of Fame and is known as one of Nebraska's greatest athletes. In 2005 the Omaha World-Herald, as part of a series on the 100 Greatest Athletes of Nebraska, named Weir the 19th best athlete in the state's history. Weir played on the offensive line at Nebraska and was an integral part (also captain) of the 1923 team that beat the "Four Horsemen" of the University of Notre Dame.
He went on to play for the Frankford Yellow Jackets of the National Football League. In 1927, he and several teammates took over the coaching job in mid-season, achieving an 6-9-3 record, as Weir earned All-Pro honors. The following year, Weir coached the team to an 11-3-2 record, good for a second-place league finish.