- NOTE: The Duke University Alumni Association considers anyone who has attended Duke for two consecutive semesters and left the University in good standing to be an alumnus.
Nobel laureatesGovernment, law, and public policy
Heads of StateCabinet members and White House staff- David Addington (J.D. 1981), chief of staff to Vice President Dick Cheney
- Claude Allen (J.D. 1990), White House domestic policy advisor
- Elizabeth Dole (A.B. 1958), United States Senator of North Carolina; former Commissioner of the Federal Trade Commission; former United States Secretary of Transportation, former United States Secretary of Labor, former President of the American Red Cross
- John P. Hannah (A.B. 1984), assistant for national security to Vice President Dick Cheney
- John Koskinen (A.B. 1961), former Deputy Director of the White House Office of Management and Budget
- Juanita M. Kreps (A.M. 1944, Ph.D. 1948), United States Secretary of Commerce, 1977-79
- Daniel Calhoun Roper (A.B. 1888), United States Secretary of Commerce under Franklin Delano Roosevelt
- Doug Sosnik (A.B. 1979), senior advisor and political director to Former President Bill Clinton
- Kenneth Starr (J.D. 1973), former United States Solicitor General, Independent Counsel during the Whitewater Affair
- Jared Weinstein (A.B. 2002), Personal Assistant to President George W. Bush
Members of Congress- Hugh Quincy Alexander (1932), Congressman from North Carolina
- Robert Franklin Armfield, Congressman from North Carolina, Lieutenant Governor of North Carolina
- Shelley Moore Capito (B.S. 1975), Congresswoman for West Virginia's 2nd district
- Elizabeth Dole (A.B. 1958), United States Senator of North Carolina; former Commissioner of the Federal Trade Commission; former United States Secretary of Transportation, former United States Secretary of Labor, former President of the American Red Cross
- Nick Galifianakis (A.B. 1951, J.D. 1953), U.S. Representative from North Carolina
- Lisa Gladden. (A.B. 1986) US Representative from Maryland
- Hannibal Lafayette Godwin, (A.B. 1897) Democratic US Representative from North Carolina
- Robin Hayes (A.B. 1967), congressman of North Carolina’s 8th district (1998-present)
- Paul B. Henry, (A.M., Ph.D. 1968) US Represtenative from Michigan and Michigan State Senator
- Henry Hyde (X. 1947), former U.S. Representative of Illinois
- Everett Jordan, (A.B.), former U.S. Senator from North Carolina
- Bob Krueger (A.M. 1959), former U.S. Representative and Senator from Texas
- Dan Lipinski (Ph.D. 1998), congressman for Illinois' 3rd district (2005-present)
- Stan Lundine (A.B. 1961), congressman from New York (1976-1987)
- Robert D. Inglis (A.B. 1981), current U.S. Representative of South Carolina
- Denise Majette (J.D. 1979), former Georgia state judge, former United States Representative of Georgia
- Ron Paul (M.D. 1961), current United States Representative from Texas and 2008 Republican Presidential candidate.
- Nick Rahall (A.B. 1971), Congressman for West Virginia
- Willis Smith (A.B, 1909, J.D. 1912), United States Senator, United States' observer at Nuremberg Trials, Speaker of North Carolina House of Representatives
Diplomats- George Venable Allen (A.B. 1920), U.S. Ambassador to Iran, 1946–1948; Assistant Secretary of State for Public Affairs, 1948–1949; U.S. Ambassador to Yugoslavia, 1949–1953.
- Robert Sherwood Dillon (A.B. 1951), U.S. Ambassador to Lebanon (1981-1983)
- Cynthia G. Efird (A.M.), U.S. Ambassador to Angola
- Robert C. Frasure, (Ph.D), U.S. Ambassador to Estonia
- Gordon D. Giffin (A.B. 1971]], U.S. Ambassador to Canada (1997-2001)
- Jack Gosnell (A.B. 1966), former US Consul General to St. Petersburg, Russia
- Richard W. Graber (A.B. 1978), United States Ambassador to the Czech Republic
- Robert Jordan (A.B. 1967), former United States Ambassador to Saudi Arabia.
- Bob Krueger (M.A. 1959), U.S. Ambassador to Burundi during administration of Bill Clinton
- Philip Lader (A.B. 1966), Ambassador to the United Kingdom and co-host of the Renaissance Weekends
- Jack F. Matlock, Jr. (A.B. 1950), United States Ambassador to Czechoslovakia and to the Soviet Union under Ronald Reagan
- Walter P. McConaughy (A.B. 1930), former United States Ambassador to Burma, South Korea, Pakistan, and Taiwan
- Elizabeth Verville (A.B. 1961), Deputy Assistant Secretary of State for Political and Military Affairs
Military- Walter E. Boomer (B.S. 1960), General, Retired, former assistant commandant, US Marine Corps, Desert Storm Commander; business executive
- Frank Bowman (B.S. 1966), Admiral, Retired, former Chief of Naval Personnel, former Director of Naval Nuclear Propulsion, US Navy; Honorary Knight Commander of the Most Excellent Order of the British Empire (KBE)
- Edward H. Deets (1979), Rear Admiral in the United States Navy
- Charles S. Hamilton (B.S. 1974), Rear Admiral in the United States Navy
- James W. Holsinger (M.D. 1964), retired Major General in the United States Army Reserve, physician, nominated to become the 18th Surgeon General of the United States
- Eric Shinseki (A.M.), former United States Army Chief of Staff
- William Atwater (MA, PhD 1982), retired Captain in the US Marines, now an author, historian, and director of the US Army Ordinance Museum.
Law- Scott Brister (A.B.), Chief Justice, Texas Supreme Court
- Robert L. Clifford (LL. B.) 1950, Associate Justice, New Jersey Supreme Court
- Ann Covington (A.B. 1963), former Chief Justice, Missouri Supreme Court
- Allyson Duncan (J.D. 1975), Judge, U.S. Court of Appeals for the 4th Circuit
- Christine M. Durham (J.D. 1971), Chief Justice of the Utah Supreme Court
- Orinda Evans (A.B. 1965), US District Court Judge
- Karen L. Henderson (A.B. 1966), US Court of Appeals
- Susan Illston (A.B. 1970), Federal Judge
- Jeffrey Lichtman (J.D. 1990) defense attorney for John Gotti, Fat Joe, and The Game
- Denise Majette (J.D. 1979), former Georgia state judge, former United States Representative of Georgia
- Paul Martin Newby (A.B. 1977), Associate Justice of the North Carolina Supreme Court
- Susan Owens (A.B. 1971), Associate Justice of the Washington State Supreme Court
- Eric Rothschild (A.B. 1989), Lead attorney for Kitzmiller v. Dover Area School District
- Don Willett (A.M. 1992, J.D. 1992), Associate Justice, Texas Supreme Court
Public policy- Gregory Baylor (J.D. 1990), religious activist, Christian Legal Society
- Charlotte Bunch (A.B. 1966) author and human rights activist
- Benjamin Chavis, Jr. (MDiv 1980), civil rights activist, executive director of the National Association for the Advancement of Colored People (NAACP)
- Mary Duke Biddle (A.B. 1907), daughter of Benjamin Newton Duke and Sarah Pearson Angier Duke, founder of the Mary Duke Biddle Foundation
- Neal Keny-Guyer (A.B. 1976), CEO of Mercy Corps
- Jerry Meek, (A.B. 1993, J.D. 1997), Chairman of the North Carolina Democratic Party
- Margaret Taylor Smith (A.B. 1947), Chair, Board of Trustees, Kresge Foundation
- Mary Duke Biddle Trent Semans (A.B. 1939), philanthropist
- Eleanor Smeal (A.B. 1961, LL.D 1991), political activist, current president of the Feminist Majority Foundation, former president of the National Organization for Women
Others- Austin M. Allran (A.B. 1974) member of the North Carolina General Assembly
- Ed Austin (A.B. 1948), Mayor of Jacksonville 1991-1995
- Michael Bassett (Ph.D. 1961), Member of the New Zealand Parliament
- Daniel T. Blue, Jr. (J.D), former member of the North Carolina House of Representatives, 1981-2002
- Samuel Bogley, (A.B), former Lieutenant Governor of Maryland
- F. Vernon Boozer, (A.B 1958), former member of Maryland Senate 1981-1999.
- Bill Campbell (J.D. 1977), Mayor of Atlanta 1994-2002
- Cason Carter (A.B. 2000), Tulsa, Oklahoma, City Council Member, 2006-present
- J. Kane Ditto (A.B.), former Mayor of Jackson, Mississippi
- J.B. Fuqua (G.Hon 1973), Chairman of the Georgia Democratic Party
- Hannibal Lafayette Godwin, (A.B. 1897) Democratic US Representative from North Carolina
- Hashim bin Al Hussein (X), Prince of Jordan
- Stan Lundine (A.B. 1961), former Mayor of Jameston, former Congressman and Lieutenant Governor of New York
- Kevin J. Martin (M.P.P. 1993), Chairman of the Federal Communications Commission
- Evelyn Murphy (A.B. 1965, Ph. D 1981), former Lieutenant Governor of Massachusetts
- Ron Paul, presidential candidate
- Enrique Peñalosa (A.B.), Mayor of Bogotá, Colombia
- Robert Sheheen (A.B. 1965), former Speaker, South Carolina House of Representatives
- Andrew Skurka (A.B. 2003), first person to walk across North America and complete the 7,700 Sea-to-Sea-Route
- Charlie Soong (X. 1881), Duke's first international student and patriarch of the Soong Dynasty
- Lura S. Tally (A.B. 1942), Member of the North Carolina House of Representatives, 1973-1983, and the North Carolina Senate, 1983-1995
- William B. Umstead (J.D 1921), Governor of North Carolina
- Bob Wise (A.B. 1970), Governor of West Virginia
- Mike Woodard (A.B. 1981), Durham, North Carolina City Council member
- Cathy Zoi (B.S. 19??), former Chief of Staff of the White House Office on Environmental Policy in the Clinton Administration, CEO of Al Gore's Alliance for Climate Protection
Business- Rex Adams (A.B. 1962), chairman of the Public Broadcasting Service (PBS), former VP of Mobil Corporation
- John A. Allison IV (M.B.A. 1974), Chairman and CEO, BB&T
- Steven Black (A.B. 1974), Co-CEO, Investment Bank, JPMorgan Chase & Co.
- Roy J. Bostock (A.B. 1962), former Chairman of B|Com3 Group, Inc., now on the board of directors for Morgan Stanley, Yahoo, and Northwest Airlines, namesake of Bostock Library
- Jack O. Bovender Jr. (1967, 1969), chairman and CEO of HCA
- Andrew Busey (B.S. 1993), creator of iChat
- Lewis B. Cambell (B.S.E 1968), CEO of Textron
- John Canning, Jr., founder of private equity firm Madison Dearborn Partners and co-owner of the Milwaukee Brewers
- John Chambers (X. 1968), CEO of Cisco Systems, attended from 1967 until 1968
- Timothy D. Cook (M.B.A.), COO of Apple Inc.
- Nola Maddox Falcone (1961), Managing Principal, NMF Asset Management
- Clay Felker (A.B. 1951), Founding Editor of New York Magazine
- Michael J. Fitzpatrick, Chairman and CEO, E-TEK Dynamics, namesake of Duke's Fitzpatrick Center for Interdisciplinary Engineering, Medicine and Applied Sciences
- J.B. Fuqua (G.Hon 1973), Chairman of the Board of The Fuqua Companies, founder of the J.B. Fuqua Foundation, namesake of Duke's Fuqua School of Business
- Melinda Gates (A.B. 1986, M.B.A. 1987), co-founder of the Bill and Melinda Gates Foundation, wife of Bill Gates
- David R. Goode (A.B. 1962), Chairman, President, & CEO of Norfolk Southern
- William H. Gross (B.S. 1966), Founder and Chief Investment Officer, PIMCO, the world's largest bond fund with $641.6 billion in assets, the owner of the only complete collection of U.S. 19th century stamps
- Bill Hawkins (B.S. 1976), CEO of Medtronic
- Betsy Holden (A.B.), CEO of Kraft Foods, 2001-2003
- Edwin L. Jones, Jr. (B.S. 1948), Engineer, president, J. A. Jones Construction Company
- Rik Kirkland (A.M. 1976), S/B Managing Editor, Fortune Magazine
- John A. Koskinen (A.B. 1961), President of US Soccer Foundation, former Deputy Director, Office of Management and Budget
- Dan Levitan (1979), Co-founder & managing partner, Maveron
- Diane Britz Lotti (1974), President of Pan Oceanic Management, Ltd.
- Gérard Louis-Dreyfus (A.B., J.D.), French billionaire businessman
- John J. Mack (A.B. 1968), CEO of Morgan Stanley, former CEO of Credit Suisse First Boston
- Aubrey McClendon (A.B. 1981) CEO, chairman, and co-founder of Chesapeake Energy. Shares principal ownership of the NBA's Seattle SuperSonics and WNBA's Seattle Storm.
- Amit Mitra (Phd, Economics 1976). Secretary General of FICCI-Federation of Indian Chambers of Commerce & Industry, India's Apex Business Chamber. Dr Mitra is also the recipient of India's Prestigious National Civilian Award " Padma Shree" conferred by the President of India in 2008
- Lalit Modi (A.B. 1986), Modi Enterprises Scion, Chairman and Founder of Indian Premier League
- Raymond Nasher (1943), Real estate developer, philanthropist, namesake of Duke's Nasher Museum of Art
- Peter Nicholas (A.B. 1964), Founder and Chairman of Boston Scientific Corporation
- Stephen Pagliuca, Part owner of the Boston Celtics, Managing Director of Bain Capital
- Edmund T. Pratt, Jr. (B.S.E. 1947), former CEO of Pfizer, philanthropist, namesake of Duke's Edmund T. Pratt School of Engineering
- Drew Rosenhaus (J.D. 1990), NFL sports agent
- David M. Rubenstein (A.B. 1970), co-founder of The Carlyle Group
- W. Russell Scheirman (A.B. 1977, M.S. 1978), President & CFO of Vaalco Energy Inc.
- Alan Schwartz (A.B. 1972), CEO, Bear Stearns
- W. David Stedman (1942), Business executive, philanthropist
- Robert K. Steel (A.B. 1973), Chairman of the Duke University Board of Trustees, President & CEO, Wachovia
- James L. Vincent (B.S. 1961), Chairman & CEO, Biogen Idec
- Jeffrey Vinik (B.S. 1981), Chairman, President, and CEO of Vinik Asset Management
- Karl von der Heyden (1962), Vice Chairman & CFO, Pepsico, Inc., namesake of the von der Heyden pavilion at Duke
- G. Richard Wagoner, Jr. (A.B. 1975), President & CEO, General Motors Corporation
- Gary L. Wilson (A.B. 1962), Director of The Walt Disney Company, Co-Chairman of Northwest Airlines, namesake of Wilson Rec Center at Duke
- Gao Xiqing (J.D. 1986), General Manager and Chief Investment Officer of the China Investment Corporation
- Harold Yoh|Harold "Spike" Yoh (B.S. 1958). Former Chairman and CEO of Day & Zimmermann, namesake of Duke's Yoh Football Center
Education- Susan Athey (A.B. 1991), professor of economics at Harvard University and winner of the John Bates Clark Medal.
- George Brumley, Jr. (A.B. 1956), former Chairman of Pediatrics, Associate Dean, Emory University
- Mauri Ditzler (Ph.D. 1979), president of Monmouth College
- David L. Downie (A.B. 1983), author, professor of politics and environment policy at Fairfield University
- David Efird (A.B. 1995), philosopher and lecturer at the University of York
- Thomas Eugene Flanagan (Ph.D), conservative Canadian political scientist
- Charles Flynn (Ph.D.), president of the College of Mount Saint Vincent
- W. Kent Fuchs (BSE) - Dean of Cornell University College of Engineering
- Pamela Gann (J.D. 1973), president of Claremont McKenna College and former Dean of Duke University School of Law
- Ken Gergen (Ph. D. 1962), notable American psychologist and professor at Swarthmore College
- Douglas Hodgkin, (Ph.D.) political scientist, author and professor at Bates College
- Frank Lentricchia, (Ph.D. 1960), literary critic, former professor of literature at Duke University
- Theodore E. Long, (A.M 1968), president of Elizabethtown College
- A. D. Kirwan (Ph. D., 1947), seventh president of the University of Kentucky
- Juanita M. Kreps (A.M. 1944, Ph.D. 1948), professor, economist, United States Secretary of Commerce
- Benjamin Ladner (Ph.D. 1970), former president of American University
- Robert L. Morris (Ph.D. 1969), notable psychologist, Koestler professor at the University of Edinburgh
- Noel Perrin (A.M., 1950), scholar, essayist, and critic. Professor at Dartmouth College
- Reynolds Price (A.B 1955), renowned author and professor of literature at Duke University
- David P. Roselle (Ph.D. 1965), President, University of Delaware
- Haun Saussy (A.B., 1981) comparative literature professor at Yale University
- David E. Sweet (Ph.D., 1968), founding president of Metropolitan State University and later president of Rhode Island College.
- Jill Tiefenthaler (A.M., Ph. D.), provost of Wake Forest University
- George Wallace (A.B. 1957), former Dean, Dartmouth Medical School
- Theodore Ziolkowski (A.B. 1951), Former Dean, The Graduate School, Princeton University
Medicine, science and technology- David H. Adams, heart valve surgery and mitral valve repair
- Lenox Baker (M.D. 1973), physician, public servant
- Lt. Andy Baldwin, The Bachelor, lieutenant, and doctor
- Ian Barbour (M.S. 1946), physicist, theologian, and recipient of the Templeton Prize in 1999
- Charles E. Brady, Jr. (M.D. 1975), astronaut
- Fred Brooks (A.B. 1953), engineer, developer of OS/360, Turing Award winner
- John C. Browne (physicist) (Ph.D.), former director of the Los Alamos National Laboratory
- Jerome Bruner (A.B. 1937), renowned psychologist and professor
- George Church (B.S. 1974), helped initiate the Human Genome Project, professor at Harvard Medical School
- John Cocke (B.S. 1945, Ph.D. 1956), considered the father of the RISC computer architecture, Turing Award laureate in 1987
- John W. Cornwell (B.S. 2006), inventor of the beer launching fridge
- William DeVries (GME 1971-1979), pioneer of artificial organs
- Sylvia Earle (Ph. D, 1966), marine biologist, Chief Scientist of the National Oceanic and Atmospheric Administration
- Jim Ellis, co-creator of Usenet with Tom Truscott
- Paul Farmer (B.S. 1982), infectious disease doctor, winner of MacArthur Award, subject of Pulitzer-prize winning author Tracy Kidder's biography Mountains Beyond Mountains
- Ken Gergen (Ph. D. 1962), notable American psychologist and professor at Swarthmore College
- John M. MacDougal (Ph. D. 1984), botanist
- Robert Morris (Ph. D 1969), notable psychologist, Koestler professor at the University of Edinburgh
- George Porter, III (A.B. 1954), Chairman Emeritus, Ochsner Medical Foundation
- Jim Scheinman, Bebo co-founder, early Friendster employee, came close to acquiring Facebook when it was very young
- Dorothy Simpson (B.S. 1947), scientist, mathematician
- Dylan Smith, Box.net Inc. founder, CFO
- William Kennedy Smith, founder of Physicians Against Land Mines
- Tom Truscott, co-creator of Usenet with Jim Ellis
- Luis von Ahn, inventor of the captcha and Google image labeler
- Olaf von Ramm (Ph.D. 1973), first patent on a 3-D ultrasound, later developed the first electronically steered matrix-array 3-D ultrasound imager
- Ge Wang, Chuck
creator
- F. Thomas Wooten, III '57, former President of the Research Triangle Institute
- James_M._Nicholson first openly homosexual surgeon at Duke University
Literature- James Armstrong (B.S. 1982), author of UNIX Secrets and other computer books
- Margaret Taylor Smith, author, social activist, Chair, Kresge Foundation
- Fred Chappell (A.B. 1961, A.M. 1964), North Carolina Poet Laureate, novelist
- Guy Davenport, author, Thasos and Ohio, National Review contributor
- Lee McGeorge Durrell (Ph. D 1979), author, television presenter, zookeeper
- Josephine Humphreys (A.B. 1967), award-winning novelist
- Mac Hyman (A.B. 1947), author of No Time for Sergeants
- Russell Kirk (A.M. 1941), author, The Conservative Mind
- Nathaniel Lande, author, filmmaker, and former creative director of TIME magazine.
- Peter Maas (A.B. 1949), author of novels The Valachi Papers and Serpico, later made into movies
- Lydia Millet (M.E.M. 1996), author of "Oh Pure and Radiant Heart," "Everyone's Pretty" and other novels.
- Noel Perrin (A.M., 1950), scholar, essayist, and critic. Professor at Dartmouth College
- Michael Peterson (A.B. 1965), author, politician, convicted of murdering his wife in 2003
- Reynolds Price (A.B 1955), renowned author and James B. Duke professor of literature at Duke
- Haun Saussy (A.B., 1981) Bird White Housum Professor of Comparative and Chinese literature at Yale
- William C. Styron, (BA.B. 1941) author, Pulitzer Prize winner
- Anne Tyler, (A.B. 1961) Pulitzer Prize-winning novelist and writer of short stories
- Dana Vachon (B.A. 2002), author of Mergers & Acquisitions
- Haim Watzman writer
Fine arts- Michael Best (A.B. 1962), Former Principal Artist of the Metropolitan Opera
- Les Brown (A.B. 1936), Musician, Les Brown & The Band of Renown, Jazz Hall of Fame Inductee 1999
- Michael Ching (A.B. 1980), composer, Memphis Opera
- Lorenz Eitner (A.B. 1940), renowned art historian
Entertainment- Andy Baldwin (B.S. 1999), The Bachelor, lieutenant, and doctor
- Jayne Brook (1982), actress, Chicago Hope
- Ryan Carnes (X. 2004), actor, Desperate Housewives, Eating Out
- Jack Coleman (A.B. 1980), actor, Heroes, Dynasty, Days of Our Lives
- Kara DioGuardi (A.B. 1993), songwriter for musicians including Carlos Santana, Kelly Clarkson and Britney Spears
- Lee McGeorge Durrell (Ph. D 1979), author, television presenter, zookeeper
- René Echevarria (A.B. 1984), producer, The 4400, Dark Angel, Now and Again; screenwriter, Star Trek: The Next Generation, Star Trek: Deep Space Nine
- Sean Flynn (X. 1963), actor and Vietnam War photojournalist
- Annabeth Gish (A.B. 1992), actress, X-Files, The West Wing
- Kelly Goldsmith (A.B. 2001), actress, Survivor
- Kevin Gray (A.B. 1980), Broadway actor, Phantom on Broadway after Michael Crawford
- John Gromada (A.B. 1986), Broadway composer and sound designer
- Jared Harris (B.F.A. 1984), actor
- Beth Hubbard (A.B. 1985), president, Gotham Entertainment Production Co.
- Ken Jeong, Comedian
- Martin Kratt (B.S. 1989), Creator and star of PBS's Zoboomafoo
- Bruce Lund (A.B. 1973), toy designer
- Tucker Max (J.D. 2001), author of the New York Times best selling book I Hope They Serve Beer in Hell, internet celebrity (TuckerMax.com)
- Ben Mulroney, host of Canadian Idol and eTalk Daily
- Laura Paresky (A.B. 1990), television designer/animator
- Charles Randolph-Wright, Director, writer, and producer
- Rebecca Sealfon, (Ph.D. 2009) internet celebrity and winner of 1997 Scripps National Spelling Bee
- Travis Lane Stork (B.S. 1994), Reality star of ABC's Bachelor 8
- Randall Wallace (A.B. 1971), Author of the screenplays for Braveheart, The Man in the Iron Mask, Pearl Harbor, and We Were Soldiers
- Patrick Williams (A.B. 1961), composer for movies and TV, Emmy and Grammy winner
Fictional- Ben Barry, a character played by Matthew McConaughey in How to Lose a Guy in 10 Days, is a Duke alumnus
- Lt. Colonel Sarah MacKenzie, USMC, a character played by Catherine Bell in the television series JAG, earned her law degree from Duke University School of Law
- Nick Savrinn, a character on Prison Break, attended Duke as an undergraduate
- Nathan Scott, a character played by James Lafferty on the television series One Tree Hill (TV series), received a scholarship to play basketball at Duke
- Sam Seaborn, a character portrayed by Rob Lowe on The West Wing, graduated from Duke University School of Law
- Stingo, the narrator of William Styron's novel Sophie's Choice, attended Duke as an undergraduate (as did Styron).
- Stacy Warner, a character played by Sela Ward on House
- Charlotte York's brother Wesley on Sex and the City
- Dr. Jim Pomatter in Waitress
Journalism and media- Dan Abrams (A.B. 1988), chief legal correspondent for NBC News, host of Verdict with Dan Abrams, former General Manager of MSNBC
- J. Bowyer Bell (doctorate 1959), historian, artist and art critic
- Dan Bernstein (A.B.), sports journalist, WSCR radio host
- John Feinstein (A.B. 1977), sports journalist
- Clay Felker (A.B. 1951), Founding Editor of New York Magazine
- Sean Flynn (X. 1963), actor and Vietnam War photojournalist
- David Hartman (A.B. 1956), first host of Good Morning America on ABC
- Mangesh Hattikudur (A.B. 2001) co-founder of mental floss with Will Pearson
- John Harwood (A.B. 1978), National Political Editor of The Wall Street Journal, frequent panelist on Washington Week
- Matt Ivester (2005), founder of JuicyCampus, a gossip website
- Scott McCartney (A.B. 1982), Travel Editor and journalist for The Wall Street Journal, author
- Sean McManus (A.B. 1977), President of CBS News and CBS Sports
- Susannah Meadows (A.B. 1995) Senior Writer for Newsweek
- Will Pearson (A.B. 2001) co-founder of mental floss with Mangesh Hattikudur
- Charlie Rose (A.B. 1964, J.D. 1968), journalist, former CBS News Anchor, 60 Minutes contributor
- Jim Rosenfield (A.B. 1981) WCBS-TV anchor
- Monty Sarhan (J.D. 1999), Publisher and CEO of national humor magazine Cracked
- John Seigenthaler, Jr. (B.S. 1978) NBC and MSNBC news anchor
- Elizabeth Spiers (A.B. 1999) founding editor of Gawker.com
- Jim Toomey (B.S.E. 1983), Syndicated cartoonist of Sherman's Lagoon
- Judy Woodruff (A.B. 1968), NBC's White House correspondent and Washington correspondent for the MacNeil/Lehrer News Hour, anchor at CNN
Athletics
- See also Duke Blue Devils men's basketball players, Duke Blue Devils women's basketball players, and Duke Blue Devils football players.
American football- Brian Baldinger (1982), former National Football League offensive lineman, current commentator for Fox
- Dave Brown (1991), ten seasons in the NFL with the New York Giants and Arizona Cardinals
- Al DeRogatis (1948), Pro Bowl tackle for the New York Giants
- Anthony Dilweg (1989), former NFL quarterback, enjoyed brief success with the Green Bay Packers
- Sonny Jurgensen, Hall of Fame quarterback who played for the Philadelphia Eagles and Washington Redskins
- Kevin Lewis, NFL linebacker
- Patrick Mannelly, NFL longsnapper
- George McAfee, Hall of Fame halfback who played for the Chicago Bears
- Scottie Montgomery, Arena Football League wide receiver/defensive back
- Clarence "Ace" Parker, Hall of Fame quarterback who played for the Brooklyn Dodgers, Boston Yanks, and New York Yankees
- Tommy Prothro, former head coach of the Los Angeles Rams and San Diego Chargers
- Drew Strojny, NFL football offensive tackle
- Ed Newman, (1973), twelve seasons in the NFL with the Miami Dolphins.
Baseball- Wayne Ambler, professional baseball player
- Bob Brower, Major League Baseball player
- Chris Capuano (2000), professional baseball player
- Claude Corbitt, professional baseball player
- Lawrence "Crash" Davis, professional baseball player (see also Bull Durham)
- Ryan Jackson, professional baseball player
- Bill McCahan, MLB player
- Quinton McCracken, professional baseball player, member of 2001 World Series Champion Arizona Diamondbacks
- Scott Schoeneweis, professional baseball pitcher, member of the 2002 World Series Champion Anaheim Angels. Currently with the New York Mets.
- Al Spangler, professional baseball player
- Eric Tipton, professional baseball player
- Mike Trombley, MLB pitcher
- Hal Wagner, professional baseball player
Basketball- Tommy Amaker, Harvard University head basketball coach
- Shane Battier, professional basketball player (jersey retired)
- Alana Beard, professional basketball player (WNBA) (jersey retired)
- Jay Bilas (A.B. 1986, J.D. 1992), ESPN sports commentator
- Carlos Boozer, professional basketball player
- Elton Brand, professional basketball player
- Jeff Capel, University of Oklahoma head basketball coach
- Chris Collins, men's basketball assistant coach
- Johnny Dawkins, Stanford University head basketball coach, associate head basketball coach and former professional basketball player (jersey retired)
- Luol Deng, professional basketball player
- Charles "Lefty" Driesell, college basketball coach
- Chris Duhon, professional basketball player
- Mike Dunleavy, Jr., professional basketball player
- Daniel Ewing, professional basketball player
- Danny Ferry, Cleveland Cavaliers general manager, former professional basketball player, member of 2003 NBA Champion San Antonio Spurs (jersey retired)
- Mike Gminski, FSN sports commentator (jersey retired)
- Dick Groat, professional baseball and basketball player (jersey retired)
- Art Heyman, former professional basketball player (jersey retired)
- Grant Hill, professional basketball player (jersey retired)
- Nick Horvath, West Sydney Razorbacks professional baseball player
- Bobby Hurley, professional basketball player (jersey retired)
- Dahntay Jones, professional basketball player
- Billy King, President and General Manager of the Philadelphia 76ers
- Christian Laettner, professional basketball player (jersey retired)
- Corey Maggette, professional basketball player
- Jeff Mullins, professional basketball player for the Golden State Warriors and head basketball coach at UNC Charlotte (jersey retired)
- Shavlik Randolph, professional basketball player
- J.J. Redick (A.B. 2006), ACC's all-time leading scorer, NCAA's all-time leader in three-point field goals, professional basketball player (jersey retired)
- Quin Snyder, former University of Missouri basketball coach
- Jim Spanarkel, former professional basketball player, commentator
- Michele Van Gorp, professional basketball player (WNBA)
- Jason Williams, professional basketball player (jersey retired)
- Shelden Williams, Duke's all-time leader in rebounds and blocked shots, professional basketball player (jersey retired)
- Steve Wojciechowski, men's basketball assistant coach
Other- Skip Alexander professional golfer
- Beth Bauer, professional golfer
- Jenny Chuasiriporn, professional golfer
- Jay Heaps, professional Major League Soccer player, on the New England Revolution
- Nancy Hogshead, Olympic gold medal winner in swimming
- Matthew Jacobs, a world renowned martial arts expert, frequently appears in Ultimate Fighting Championship
- Liz Janangelo, professional golfer
- John Kerr, soccer player, winner of Hermann Trophy for top collegian, first American player in the Football League First Division (now known as the Premiership), Duke's head coach
- Jason Kreis professional soccer player
- Joe Ogilvie, professional golfer
- Mike Souchak, professional golfer, winner of 15 PGA events
- Becca Ward, 2008 Olympic Bronze Medalist
- Art Wall, Jr., professional golfer, winner of 1959 Masters
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